Current Understanding of Atrophic Gastritis and Intestinal Metaplasia as a Premalignant Lesion of Gastric Cancer

Review of Atrophic Gastritis and Intestinal Metaplasia as a Premalignant Lesion of Gastric Cancer

Atrophic gastritis (AG) and intestinal metaplasia (IM) are the main precursor lesions of gastric cancer as the incidence of gastric cancer increases in the gastric mucosa involved with AG and IM. The prevalence of AG and IM vary depending on countries, even it represents diverse results in the same nation. Usually AG is antecedent of IM but the etiologies of AG and IM are not always the same. T...

Accuracy of pepsinogens for early diagnosis of atrophic gastritis and gastric cancer in Iranian population

  Background: Currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. The purpose of this study was to evaluate the value of serological parameters including serum pepsinogen I (PGI), pepsinogen II (PGII) and pepsinogen I: II ratio for the screening atrophic gastritis and gastric cancer.   Methods : The study population consisted of 132 dyspeptic patient...

Magnifying Endoscopy and Chromoendoscopy in Atrophic Gastritis, Intestinal Metaplasia and Gastric Dysplasia

Associations among Gastric Juice pH, Atrophic Gastritis, Intestinal Metaplasia and Helicobacter pylori Infection

Background/Aims Gastric juice plays a crucial role in the physiology of the stomach. The aim of this study is to evaluate associations among the pH of gastric juice, atrophic gastritis (AG), intestinal metaplasia (IM), pepsinogen, and Helicobacter pylori infection. Methods Gastric biopsies and juice were collected from 46 subjects who underwent endoscopies at Seoul National University Bundang...

مقایسه موسین موجود در سلولهای مخاط معده بیماران مبتلا به گاستریت هلیکوباکترپیلوری با افراد طبیعی

ABSTRACT Gastric cancer (GC) is one of the most common cancers in the world. Despite some improvement in the treatment of this type of cancer, the 5-year survival rate has been already remained low. Therefore further exploration of biological features and causes of gastric cancer is needed to reduce its occurrence. In sequential changes from superficial gastritis to dysplasia and cance...